Purpose Artificial Intelligence (AI) holds the potential for improving dental hygiene clinical practice as well as dental hygiene education. The purpose of this study was to identify educators’ perspectives, attitudes, and concerns about the implementation of AI in dental hygiene education and students’ preparedness for clinical practice.Methods This study used an exploratory qualitative design with a purposive sample of dental hygiene educators from the United States. Virtual interviews were conducted using an interview guide during the fall 2024 and spring 2025. Recorded interview sessions lasted an average of 45 minutes and were transcribed to an encrypted, password-protected account. Data were analyzed using qualitative research software. Responses were coded and categorized into emerging themes and sub themes. A pilot interview, member checks, and investigator triangulation were used to establish validity and reliability.Results Twenty-two dental hygiene educators from across the United Staes participated in the study. The themes identified were Informed, Misgivings, Resources, Academic Integrity, Implementation, and Professional Assimilation. Subthemes for Misgivings included Intellectual Deterioration and Neophobia while Subthemes for Academic Integrity were Misuse and Guidelines.Conclusion Formalized training and resources related to dental hygiene education and ethical guidelines are needed to implement AI in didactic and clinical instruction. Additional studies identifying dental hygiene students’ preferences and understanding of AI and methods for implementing AI in clinical education to prepare students for practice are needed.